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Stephen D. Miller: Faculty Experts

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Stephen D. Miller

Northwestern University Feinberg School of Medicine

Professor Emeritus of Microbiology-Immunology


Areas of Focus

  • Autoimmune disease
  • Allergy
  • Transplantation
  • Immunoregulation
  • Inflammation


  • Understanding the pathogenesis of autoimmune and allergic diseases
  • Regulation of autoimmune and allergic diseases using antigen-specific therapies
  • Drug delivery using nanomedicine approaches
  • Regulation of acute inflammation using biodegradable nanoparticles


Dr. Stephen Miller received his Ph.D. in 1975 from the Pennsylvania State University and did postdoctoral training at the University of Colorado Health Sciences Center before joining the faculty at Northwestern in 1981 where he currently serves as Director of the Northwestern University Interdepartmental Immunobiology Center. Dr. Miller is internationally recognized for his research on pathogenesis and regulation of autoimmune diseases. He has published over 415 journal articles, reviews and book chapters and has trained multiple generations of scientists. His work has significantly enhanced understanding of immune inflammatory processes underlying chronic autoimmune disease employing animal models of multiple sclerosis (MS), Type 1 diabetes (T1D) and celiac disease (CD). His work has focused on the study of the cellular and molecular mechanisms underlying treatment of established T cell-mediated autoimmune diseases using antigen-specific immune tolerance. His current work is geared to translating the use of antigen-linked biodegradable PLG nanoparticles for the treatment of human immune-mediated diseases including autoimmunity, allergy, protein and gene replacement therapy, and tissue/organ transplantation.