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Neil Kelleher: Faculty Experts

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Neil Kelleher

Weinberg College of Arts and Sciences

Professor and Director Proteomics
Director of the Chemistry of Life Processes Institute
Department of Chemistry, Department of Molecular Biosciences
Weinberg College of Arts and Sciences (also Feinberg School of Medicine)


Areas of Focus

  • Top-down proteomics
  • Natural products biosynthesis/discovery
  • Chromatin biology
  • Mass spectrometry


  • Protein biomarkers of health and disease
  • Top-Down Proteomics and the Human Proteoform Project: we are at the leading edge of the growing calls for a national project to characterize all of the proteoforms, specific molecular forms of proteins, in the human body and develop them as markers and targets in human disease.
  • Metabologenomics: we combined genome sequencing and automated gene cluster prediction with mass spectrometry-based metabolomics to detect new natural products and correlate them with their biosynthetic gene clusters on a large-scale
  • Technology development and applications for high performance mass spectrometry at the interface of chemistry and biology
  • Complex mixture analysis using Fourier-Transform Mass Spectrometry for targeted applications in proteomics and natural products