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Karla Satchell: Faculty Experts

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Karla Satchell

Northwestern University Feinberg School of Medicine

Anne Stewart Youmans Professor, Professor of Microbiology-Immunology
Principal Investigator and Co-Director of the Center for Structural Genomics of Infectious Diseases

About

Areas of Focus

  • Microbiology
  • Bacteria
  • Structural biology
  • Cholera
  • Vibrio vulnificus
  • Coronavirus
  • Bacterial toxins

Work/Research

  • Uses combination of microbiology, biochemistry, cell biology and structural biology to study infectious disease mechanisms
  • Studies the mechanism by which the bacterium that causes cholera hides from the host immune system
  • Studies how Vibrio vulnificus bacteria cause human disease resulting in rapid death following seafood consumption
  • Discovered how a novel RAS degrader protein from bacteria can be repurposed to treat cancer
  • Protein structure and drug development for SARS-CoV-2 and other viruses with pandemic potential

Career

Dr. Satchell leads the Center for Structural Biology of Infectious Diseases, a multi-site center studying antimicrobial resistance, viruses with pandemic potential, and microbial pathogenesis.  She is a fellow of the American Association of Microbiology and the American Association for the Advancement of Science and has been recognized as a Burroughs Wellcome Fund Investigator of Pathogenesis of Infectious Diseases.