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Dr. John Pandolfino: Faculty Experts

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Dr. John Pandolfino

Northwestern University Feinberg School of Medicine

Hans Popper Professor of Medicine
Division Chief, Gastroenterology and Hepatology


Areas of Focus

  • Esophageal disorders
  • Swallowing disorders
  • Gastroesophageal Reflux Disease (GERD)
  • Eosinophilic esophagitis


  • Defining normal and abnormal esophageal function by using physiology, principles of biomechanics, mathematical modeling and in-silico simulations 
  • Developing new tools to better understand esophageal diseases
  • Developing better biomarkers of esophageal disease severity and discovering new targets for therapy 
  •  Ultimate goal is to develop a universal model that connects the molecular perturbations that lead to abnormal esophageal bolus transport and describe how these mechanical changes lead to symptoms and reduced quality of life.