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Dr. Crystal Jing Jing Yeo
Northwestern University Feinberg School of Medicine
Adjunct Associate Professor of Neurology (Neuromuscular Medicine)
About
Areas of Focus
- Neuromuscular medicine
- Motor neuron disease
- Spinal muscular atrophy (SMA)
- Amyotrophic lateral sclerosis (ALS)
- Diagnostic and prognostic biomarkers
Work/Research
- Studies the basic biological mechanisms of neuromuscular diseases – particularly SMA and ALS – and their direct applications to patient care and drug discovery
- Uses large clinical databases to determine diagnostic and prognostic biomarkers
- Works to define appropriate therapeutic windows and cell targets for SMN protein augmenting therapies and decide on therapeutic regimes to treat the entirety of SMA pathology
- Works to predict fast ALS disease progressors, which can enrich clinical trials with patients most likely to demonstrate treatment effect over a restricted time-period