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Dr. Crystal Jing Jing Yeo

Northwestern University Feinberg School of Medicine

Adjunct Associate Professor of Neurology (Neuromuscular Medicine)


Areas of Focus

  • Neuromuscular medicine
  • Motor neuron disease
  • Spinal muscular atrophy (SMA)
  • Amyotrophic lateral sclerosis (ALS)
  • Diagnostic and prognostic biomarkers


  • Studies the basic biological mechanisms of neuromuscular diseases – particularly SMA and ALS – and their direct applications to patient care and drug discovery
  • Uses large clinical databases to determine diagnostic and prognostic biomarkers
  • Works to define appropriate therapeutic windows and cell targets for SMN protein augmenting therapies and decide on therapeutic regimes to treat the entirety of SMA pathology
  • Works to predict fast ALS disease progressors, which can enrich clinical trials with patients most likely to demonstrate treatment effect over a restricted time-period